Upstate KIDS CVD Follow-up Support - Second Phase

This study examines whether childhood health, particularly of cardio-metabolic risk, through age 8 years differs by infertility treatment exposure.

Title: Upstate Kids CVD Follow-up Support - Option 2

Principal Investigators: Lina Mu, MD, PhD, and Richard Browne, PhD

Funding Agency: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institutes of Health (NIH)

Period: 08/01/16 - 03/31/17

Abstract: This project is a subcontract from a study by Erin Bell, PhD, from the University at Albany School of Public Health.

The Upstate KIDS Study tracks the growth, motor, and social development of children given the increasing use of infertility treatment, occurrence of maternal obesity and pregnancy complications, and rising maternal age at birth. From 2008 to 2010, over 5000 mothers and their 6000 children born from the 57 counties of New York State (exclusive of New York City) joined this important study!

The First Phase: Neurodevelopment. First follow-up phase by questionnaires occurred at 4, 8, 12, 18, 24, 30, and 36 months of age. A subgroup of 600 infants has been evaluated at age 36-48 months for neurodevelopmental impairment. In addition, with parental consent obtained at the 8-month screening, residual dried blood samples (punches) from Guthrie cards were harvested and analyzed for 5 panels of inflammatory and environmental chemical biomarkers.

This study is the Second Phase: Heart Follow-Up. The aim of the second follow-up is to determine whether childhood health, particularly of cardio-metabolic risk, through age 8 years differs by infertility treatment exposure. Parents will receive annual questionnaires and be invited for clinical exams and saliva collection programs.

See the study website for more information.