Education
BS, Human Nutrition, magna cum laude, University of Michigan - Ann Arbor, 1975
RD, Lutheran General Hospital, Park Ridge, Illinois, 1977
MS, Nutritional Sciences, University of Wisconsin - Madison, 1984
MS, Preventive Medicine (Epidemiology), University of Wisconsin - Madison, 1986
PhD, Nutritional Sciences, University of Wisconsin - Madison, 1986
Professional Training
Intern, Clinical Nutrition, Lutheran General Hospital, Park Ridge, Illinois, 1976-1977
Postdoctoral Fellow, Cancer Epidemiology, Department of Social and Preventive Medicine, State University of New York at Buffalo, 1987-1988
Profile
Dr. Freudenheim received her PhD in Nutritional Sciences from the University of Wisconsin-Madison. She subsequently came to UB for postdoctoral training in cancer epidemiology and was appointed to the faculty in the Department of Social and Preventive Medicine in 1987. Dr. Freudenheim became Interim Chair of the Department in 2003 and Chair in 2006. She is also Professor in the Department of Cancer Pathology and Prevention at Roswell Park Cancer Institute.
Research Interests
Dr. Freudenheim's research focuses on the molecular epidemiology of breast cancer. With her research group, she is examining how molecular characteristics of tumors may vary with dietary, genetic and other exposures. Dr. Freudenheim's work also includes research on the impact of exposures in early life on breast cancer risk. Her studies are conducted in Western New York and in Puerto Rico.
Selected Publications
- Freudenheim JL, Marshall, JR, Graham S, Hellmann R, Vena JE, Bandera E, Muti P, Swanson M, Nemoto T. Exposure to breastmilk in infancy and the risk of breast cancer. Epidemiol 1994;5:324-31.
- Freudenheim JL, Marshall JR, Vena JE, Laughlin R, Brasure JR, Swanson MK, Nemoto T, Graham S. Premenopausal breast cancer risk and intake of vegetables, fruits and related nutrients. J Natl Cancer Inst 1996;88:340-348.
- Ambrosone CB, Freudenheim JL, Graham S, Marshall JR, Vena JE, Brasure JR, Michalek AM, Laughlin R, Nemoto T, Gillenwater KA, Harrington AM, Sheilds PG. Cigarette smoking, N-acetyltransferase genetic polymorphisms and breast cancer risk. JAMA 1996;276:1494-501.
- Freudenheim JL, Ambrosone CB, Moysich KB, Vena JE, Graham S, Marshall JR, Muti P, Laughlin R, Nemoto T, Harty LC, Crits GA, Chan AWK, Shields P. Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer. Cancer Causes Control 1999;10:369-7.
- Freudenheim JL, Bonner M, Krishnan S, Ambrosone CB, Graham S, Vena JE, McCann SE, Moysich KB, Bowman E, Nemoto T, Shields PG. Diet and alcohol consumption in relation to p53 mutational spectra in breast tumors. Carcinogenesis 2004;25:931-9.
- Bonner MR, Han D, Nie J, Rogerson P, Vena JE, Vito D, Muti P, Trevisan M, Nemoto T, Edge S, Freudenheim JL. Breast Cancer Risk and Exposure in Early Life to Polycyclic Aromatic Hydrocarbons Using Total Suspended Particulates as a Proxy Measure. Ca Epi Biomarkers Prev 2005;14:53-60.
- Freudenheim JL, Ritz J, Smith-Warner SA, Albanes D, Bandera EV, van den Brandt PA, Colditz G, Feskanich D, Goldbohm RA, Harnack L, Miller AB, Rimm E, Rohan TE, Sellers TA, Virtamo J, Willett WC, Hunter DJ. Alcohol consumption and risk of lung cancer: a pooled analysis of cohort studies. Am J Clin Nutr 2005;82:657-67.
- Dumitrescu RG, Marian C, Krishnan SS, Spear SL, Kallakury BVS, Perry DJ, Convit JR, Seillier-Moiseiwitsch F, Yang Y, Freudenheim JL, Shields PG. Familial and Racial Determinants of Tumor Suppressor Genes Promoter Hypermethylation in Breast Tissues from Healthy Women. J Cellular Molec Med 2010;14:1468-75.
- McCann SE, Thompson LU, Nie J, Dorn J, Trevisan M, Shields PG, Ambrosone CB, Edge SB, Li H-F, Kasprzak C, Freudenheim JL. Dietary lignan intakes in relation to survival among women with breast cancer: the Western New York Exposures and Breast CancerC(WEB) Study. Br Ca Res Treatment 2010;110:229-35.
- Brasky TM, Bonner MR, Moysich KB, Ambrosone CB, Nie J, Tao MH, Edge SB, Kallakury BVS, Marian B, Trevisan M, Shields PG, Freudenheim JL. Non-steroidal anti-inflammatory drug (NSAID) use and breast cancer risk in the Western New York Exposures and Breast Cancer (WEB) study. Cancer Causes and Control 2010; 21:1503-12.
- Jaworowicz DJ, Nie J, Bonner M, Han D, Vito D, Hutson A, Potischman N, Trevisan M, Muti P, Freudenheim JL. Agreement between self-reported birth weight and birth certificate weights and case control status. J Develop Origins Health Disease 2010;1:106-13.
- Tao MH, Shields PG, Nie J, Marian C, McCann SE, Millen A, Ambrosone C, Hutson A, Edge SB, Krishnan SS, Xie B, Winston J, Vito D, Russell M, Nochajski T, Trevisan M, Freudenheim JL. Alcohol consumption in relation to aberrant DNA methylation in breast tumors. Alcohol 2011;45:689-699.
- Roberts M, Shields PG, Ambrosone BC, Nie J, Marian C, Amend KL, Trevisan M, Edge SB, Freudenheim JL. Single nucleotide polymorphisms in DNA repair genes and association with breast cancer risk in the WEB study. Carcinogenesis 2011;32:1223-30.
- Tao MH, Marian C, Nie J, Ambrosone C, Krishnan AA, Edge SB, Trevisan M, Shields PG, Freudenheim JL. Body mass and DNA promoter methylation in breast tumors in the Western New York Exposures and Breast Cancer (WEB) study. Am J Clin Nutr 2011; 94:831-8.
Professional Affiliations
American Association for Cancer Research (Women in Cancer Research, Molecular Epidemiology Group), American College of Epidemiology (Fellow), American Epidemiological Society, American Dietetic Association, American Society for Nutrition, Developmental Origins of Health and Disease Society, Society for Epidemiologic Research
Faculty Links
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