Education
BS, Human Nutrition, magna cum laude, University of Michigan - Ann Arbor, 1975
RD, Lutheran General Hospital, Park Ridge, Illinois, 1977
MS, Nutritional Sciences, University of Wisconsin - Madison, 1984
MS, Preventive Medicine (Epidemiology), University of Wisconsin - Madison, 1986
PhD, Nutritional Sciences, Statistics, University of Wisconsin - Madison, 1986
Professional Training
Intern, Clinical Nutrition, Lutheran General Hospital, Park Ridge, Illinois, 1976-1977
Postdoctoral Fellow, Cancer Epidemiology, Department of Social and Preventive Medicine, State University of New York at Buffalo, 1987-1988
Profile
Dr. Freudenheim received her PhD in Nutritional Sciences from the University of Wisconsin-Madison. She came to UB for postdoctoral training in cancer epidemiology and was appointed to the faculty in the Department of Social and Preventive Medicine in 1987. Dr. Freudenheim became Interim Chair of the Department in 2003 and Chair in 2006. She is also Professor in the Department of Cancer Pathology and Prevention at Roswell Park Cancer Institute.
Research Interests
Dr. Freudenheim's research focuses on diet and alcohol consumption in relation to cancer, particularly breast cancer. With her research group, she is working also on understanding how genetic factors may interact with diet to influence disease risk, on how tumor characteristics may vary with dietary, genetic and other exposures and on the impact of exposures in early life on breast cancer risk. Her work includes studies in Western New York and in Puerto Rico.
Selected Publications
- Freudenheim JL, Marshall, JR, Graham S, Hellmann R, Vena JE, Bandera E, Muti P, Swanson M, Nemoto T. Exposure to breastmilk in infancy and the risk of breast cancer. Epidemiol 1994;5:324-31.
- Freudenheim JL, Marshall JR, Vena JE, Laughlin R, Brasure JR, Swanson MK, Nemoto T, Graham S. Premenopausal breast cancer risk and intake of vegetables, fruits and related nutrients. J Natl Cancer Inst 1996;88:340-348.
- Ambrosone CB, Freudenheim JL, Graham S, Marshall JR, Vena JE, Brasure JR, Michalek AM, Laughlin R, Nemoto T, Gillenwater KA, Harrington AM, Sheilds PG. Cigarette smoking, N-acetyltransferase genetic polymorphisms and breast cancer risk. JAMA 1996;276:1494-501.
- Freudenheim JL, Ambrosone CB, Moysich KB, Vena JE, Graham S, Marshall JR, Muti P, Laughlin R, Nemoto T, Harty LC, Crits GA, Chan AWK, Shields P. Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer. Cancer Causes Control 1999;10:369-7.
- Freudenheim JL, Bonner M, Krishnan S, Ambrosone CB, Graham S, Vena JE, McCann SE, Moysich KB, Bowman E, Nemoto T, Shields PG. Diet and alcohol consumption in relation to p53 mutational spectra in breast tumors. Carcinogenesis 2004;25:931-9.
- Han D, Rogerson PA, Nie J, Bonnner MR, Vena JE, Vito D, Muti P, Trevisan M, Edge SB, Freudenheim JL. Geographic Clustering of Residence in Early Life and Subsequent Risk of Breast Cancer. Cancer Causes Control 2004;15:921-29.
- Bonner MR, Han D, Nie J, Rogerson P, Vena JE, Vito D, Muti P, Trevisan M, Nemoto T, Edge S, Freudenheim JL. Breast Cancer Risk and Exposure in Early Life to Polycyclic Aromatic Hydrocarbons Using Total Suspended Particulates as a Proxy Measure. Ca Epi Biomarkers Prev 2005;14:53-60.
- Freudenheim JL, Smith-Warner SA, Spiegelman D, Yaun S-S, Adami H-O, Beeson WL, van den Brandt PA, Fraser GE, Goldbohm RA, Graham S, Kushi LH, Miller AB, Potter JD, Rohan TE, Speizer FE, Toniolo PG, Willett WC, Wolk A, Zelenivich-Jacquotte A, Hunter DJ. Alcohol and lung cancer: a pooled analysis of cohort studies. Am J Clin Nutr 2005;82:658-67.
- McCann SE, McCann WE, Hong CC, Marshall JR, Edge SB, Trevisan M, Muti P, Freudenheim JL. Dietary patterns related to glycemic index and load and risk of pre- and postmenopausal breast cancer in the Western New York Exposures and Breast Cancer (WEB) study. Am J Clin Nutr 2007;86:465-71.
- Quick SK, Shields PG, Nie J, Platek M, Ambrosone CB, Hutson AD, McCann SE, Muti P, Trevisan M, Vito D, Edge S, Freudenheim JL. Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk. Ca Epidemiol Biomarkers Prev 2008;17:1082-7.
- Chanda P, Sucheston L, Zhang A, Brazeau D, Freudenheim JL, Ambrosone C, Ramanathan M. Ambience: A novel algorithm for identifying and visualizing informative genetic and environment interactions associated with complex disease phenotypes. Genetics 2008:180:1191-210.
Professional Affiliations
American Association for Cancer Research (Women in Cancer Research, Molecular Epidemiology Group), American College of Epidemiology (Fellow), American Epidemiological Society, American Dietetic Association, American Society for Nutrition, Developmental Origins of Health and Disease Society, Society for Epidemiologic Research
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