Osteoarthritis
ABSTRACTS
PREVIOUS GRANTS
NM Fisher (Principal Investigator, Faculty Preceptor
for James Graham). Rheumatology-Related Health Professional
Graduate Student Research Preceptorship for "Effects of Resistance
Training on Strength, Endurance and EMG Activity in Individuals
with Knee Osteoarthritis". American College of Rheumatology
Research and Education Foundation. $4,000, 7/02-9/02.
DR Pendergast, GE Gresham and NM Fisher (Project
Director). Progressive Quantitative Exercise in Arthritis
of the Knees. National Institute of Disability and Rehabilitation
Research, US Department of Education, #H133A80002, $501,597, 1988-1991.
PUBLISHED ABSTRACTS
Fisher
NM. Effects
of Three Exercise Rehabilitation Programs on the Relationship between
Muscular Strength and Efficiency in Knee Osteoarthritis.
Arthritis Rheum 52(9)Suppl:S434, 2005.
Fisher NM,
DM Dolan, C Brenner, DR Pendergast. Quantitative Effects of
a Water Exercise Program on Functional and Physiological Capacity
in Subjects with Osteoarthritis: a Pilot Study. Sport Sciences
for Health 1(1):17-24, 2004
Graham
J, N Fisher. Effects of Resistance Training on Muscle Function
in Individuals with Knee Osteoarthritis. Arthritis &
Rheumatism 48(9) suppl: S445, 2003.
Fisher
NM and DR Pendergast. Reduced Muscle Function in Patients
with Osteoarthritis . Scand J Rehab Med 29:213-221, 1997.
Fisher
NM, SC White, HJ Yack, RJ Smolinski and DR Pendergast. Muscle
Function and Gait in Patients with Knee Osteoarthritis before and
after Muscle Rehabilitation. Disability Rehabil 19(2):47-55,
1997.
Fisher
NM and DR Pendergast. Application of Quantitative and Progressive
Exercise Rehabilitation to Patients with Osteoarthritis of the Knee
. Journal of Back and Musculoskeletal Rehabilitation 5:33-53,
1995.
Fisher
NM and DR Pendergast. Effects of a Muscle Exercise Program
on Exercise Capacity in Subjects with Osteoarthritis . Arch
Phys Med Rehabil 75(7):792-797, 1994.
Fisher
NM, VD Kame, L Rouse and DR Pendergast. Quantitative Evaluation
of a Home Exercise Program on Muscle and Functional Capacity of Patients
with Osteoarthritis. Am J Phys Med Rehabil 73:413-420, 1994.
Fisher
NM, GE Gresham and DR Pendergast. Quantitative Progressive
Exercise Rehabilitation (QPER) for Osteoarthritis of the Knee .
Physical Medicine and Rehabilitation Clinics of North America 5(4):785-802,
1994.
Leddy
JJ, NM Fisher, RJ Smolinski, YK Barodawala, P Pandya and DR Pendergast.
Effects of Exercise Rehabilitation on Muscle Function, Activity
and Joint Spaces in Patients with Osteoarthritis. Med Sci
Sports Exerc 26(suppl):S142, 1994.
Fisher
NM, GE Gresham and DR Pendergast. Effects of a quantitative
progressive rehabilitation program applied unilaterally to the osteoarthritic
knee. Arch Phys Med Rehabil 74(12):1319-1326, 1993.
Fisher
NM, GE Gresham, M Abrams, J Hicks, D Horrigan and DR Pendergast. Quantitative
effects of physical therapy on muscular and functional performance
in subjects with osteoarthritis of the knees . Arch Phys
Med Rehabil 74(8):840-847, 1993.
Fisher
NM, SC White, JH Yack, RJ Smolinski and DR Pendergast. Muscle
Function and Gait in Patients with Knee Osteoarthritis before and
after Muscle Rehabilitation. Arch Phys Med Rehabil 73(10):972,
1992.
Fisher
NM, DR Pendergast, GE Gresham and E Calkins. Muscle rehabilitation:
its effect on muscular and functional performance of patients with
knee osteoarthritis . Arch Phys Med Rehabil 72(6):367-374,
1991.
Pendergast
DR, VD Kame Jr, L Rouse and NM Fisher. Quantitative Evaluation
of a Physical Therapy Supervised Home Exercise Program on Muscle and
Functional Capacity of Patients with Osteoarthritis. Arch
Phys Med Rehabil 72:792, 1991.
Fisher NM, VD Kame Jr and DR Pendergast. Effects of Muscle
Rehabilitation on Cardiovascular Fitness in Patients with Osteoarthritis.
Gerontologist 31(Special Issue II):9, 1991.
Maximal aerobic power has been shown to decrease with age and to be even lower in patients with osteoarthritis (OA). Patients with OA have also been shown to have reduced muscle function. The purpose of the present study was to determine if patients with OA who underwent only muscle rehabilitation had improved cardiovascular fitness. The subjects were given a maximal graded exercise test prior to and after 3 months of muscle rehabilitation. The exercise program consisted of isometric, isotonic, and endurance knee flexion and extension contractions, 3 times per week. Maximal strength and endurance improved significantly with this protocol. Maximal aerobic power increased from 13.0 +/- 2.5 ml/kg to 20.0 +/- 4.0 ml/kg, while maximal walking speed increased from 2.5 mph to 3.0 mph and exercise time increased from 9.3 +/- 1.5 minutes to 14.3 +/- 3.2 minutes. Although maximal heart rate and systolic blood pressure (SBP) did not increase, the heart rate (15 b/min) and SBP (20 mm Hg) at specific V02s was less. It would appear that the reduction in aerobic fitness of patients with OA is secondary to their reduced muscle function, and can be improved through muscle rehabilitation.
Fisher
NM, DR Pendergast and GE Gresham. Reduced Muscle and Functional
Performance in Patients with Osteoarthritis. Arch Phys Med
Rehabil 71:783, 1990.
Fisher
NM, DR Pendergast and GE Gresham. Progressive Quantitative
Rehabilitation of Patients with Osteoarthritis. Arch Phys
Med Rehabil 71:762, 1990.
Book Chapters
Fisher NM. Chapter 10: Osteoarthritis Rheumatoid Arthritis,
and Fibromyalgia. ACSM's Resources for Clinical Exercise
Physiology: Musculoskeletal, Neuromuscular, Neoplastic, Immunologic,
and Hematologic Conditions. JN Meyers, WG Herbert, R Humphrey (Eds).
Lippincott Williams & Wilkins: Baltimore, pgs. 111-124, 2002.
Fisher NM and DR Pendergast. Chapter 16: Quantitative Progressive
Exercise Rehabilitation (QPER): Rehabilitation of Patients with
Osteoarthritis. In: Key Aspects of Caring for the Chronically
Ill. Hospital and Home. SG Funk, EM Tornquist, MT Champagne and
RA Wiese (Eds). Springer Publishing Co., pgs. 178-189, 1993.
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