Physiological Mechanisms of a Biomarker of Recovery from Concussion

This study will determine if exercise intolerance in concussion patients is due to low cardiac output or changes in skeletal muscle metabolism.

Principal InvestigatorJohn J. Leddy, MD

Co-PIBlair Johnson, PhD

Funding Agency: National Institutes of Health

Period: 4/1/2016 - 3/31/2021

Abstract: We have shown that concussion patients have exercise intolerance. The goal of this project is to determine if exercise intolerance in concussion patients is due to low cardiac output or changes in skeletal muscle metabolism.