Jo L. Freudenheim
PhD
SUNY Distinguished Professor
Research Topics/Projects
Cancer epidemiology, using epidemiologic tools to understand carcinogenesis at the population, individual, tissue and molecular levels in order to better prevent and control the disease. Recent projects include a study of the breast microbiome and a study of DNA methylation in lung tissues from smokers, non-smokers and electronic cigarette users.
Contact Information
Faculty Links
Selected Publications
- Callahan CL, Bonner MR, Nie J, Wang Y, Tao MH, Shields PG, Marian C, Eng KH, Trevisan M, Freudenheim JL. Active and secondhand smoke exposure throughout life and DNA methylation in breast tumors. Ca Causes Control 2019;30:53-62. PMID: 30617699.
- Tsai M, Song M-A, McAndrew C, Brasky TM, Freudenheim JL, Mathé E, McElroy J, Reisinger SA, Shields PG, Wewers MD. Electronic vs. combustible cigarette effects on inflammasome component release into human lung. Am J Respir Crit Care Med 2019;199:922-25. PMID: 30608866.
- Truesdell E, Schelske-Santos M, Nazario CM, Rosario-Rosado RV, McCann SE, Millen AE, Ramirez-Marrero FA, Freudenheim JL. Contribution of foods to intake of macronutrients in the Puerto Rican diet. Nutrients 2018;10:E1242. PMID: 23690776.
- DiVita MA, Granger CV, Goldstein R, Niewczyk PM, Freudenheim JL. Mandated quality of care metrics for Medicare patients: Examining new or worsened pressure ulcers and rehabilitation outcomes in United States inpatient rehabilitation facilities. Arch Phys Med Rehab 2018;99:1514-24. PMID: 29649450.
- Pearlman R, Frankel WL, Swanson B, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Liyanarachchi S, Kalady M, Heald B, Greenwood C, Paquette I, Prues M, Draper DJ, Lindeman C, Kuebler JP, Reynolds K, Brell JM, Shaper AA, Mahesh S, Buie N, Weeman K, Shine K, Haut M, Edwards J, Bastola S, Wickham K, Khanduja KS, Zacks R, Pritchard CC, Shirts BH, Jacobson A, Allen B, de la Chapelle A, Hampel H; Ohio Colorectal Cancer Prevention Initiative Study Group. Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. JAMA Oncol. 2017 Apr 1;3(4):464-471. doi: 10.1001/jamaoncol.2016.5194. PMID: 27978560.
- Mix JM, Granger CV, LaMonte MJ, Niewczyk P, DiVita MA, Goldstein R, Yates JW, Freudenheim JL. A Characterization of Cancer Patients in Inpatient Rehabilitation Facilities: A Retrospective Cohort Study. Arch Phys Med Rehabil. 2017 May;98(5):971-980. doi: 10.1016/j.apmr.2016.12.023. Epub 2017 Feb 1. PMID: 28161317.
- Freudenheim JL, Genco RJ, LaMonte MJ, Millen AE, Hovey KM, Mai X, Nwizu N, Andrews CA, Wactawski-Wende J. Periodontal disease and breast cancer: Prospective cohort study of postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2016;25(1): 43-50. PMID: 26689418.
- Minlikeeva AN, Browne RW, Ochs-Balcom HM, Marian C, Shields PG, Trevisan M, Krishnan S, Modali R, Seddon M, Lehman T, Freudenheim JL. Single-nucleotide polymorphisms and markers of oxidative stress in healthy women. PLoS One. 2016;11(6):e0156450. PMID: 27271305.
- Hassinger AB, Garimella S, Wrotniak BH, Freudenheim JL. The current state of the diagnosis and management of acute kidney injury by pediatric critical care physicians. Pediatr Crit Care Med. 2016;17(8):e362-70. PMID: 27500629.
- Weaver AM, McCann SE, Nie J, Edge SB, Nochajski TH, Russell M, Trevisan M, Freudenheim JL. Alcohol intake over the life course and breast cancer survival in Western New York Exposures and Breast Cancer (WEB) Study: Quantity and Intensity of Intake. Br Ca Res Treat. 2013;139:245-53. PMID: 23605086.
- Tao MH, Shields PG, Nie J, Marian C, McCann SE, Millen A, Ambrosone C, Hutson A, Edge SB, Krishnan SS, Xie B, Winston J, Vito D, Russell M, Nochajski T, Trevisan M, Freudenheim JL. Alcohol consumption in relation to aberrant DNA methylation in breast tumors. Alcohol. 2011;45:689-699. PMID: 21168302.
- Freudenheim JL, Ambrosone CB, Moysich KB, Vena JE, Graham S, Marshall JR, Muti P, Laughlin R, Nemoto T, Harty LC, Crits GA, Chan AWK, Shields P. Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer. Cancer Causes Control. 1999;10:369-7. PMID: 10530606.
- Ambrosone CB, Freudenheim JL, Graham S, Marshall JR, Vena JE, Brasure JR, Michalek AM, Laughlin R, Nemoto T, Gillenwater KA, Harrington AM, Sheilds PG. Cigarette smoking, N-acetyltransferase genetic polymorphisms and breast cancer risk. JAMA. 1996;276:1494-501. PMID: 8903261.
- Freudenheim JL, Marshall JR, Vena JE, Laughlin R, Brasure JR, Swanson MK, Nemoto T, Graham S. Premenopausal breast cancer risk and intake of vegetables, fruits and related nutrients. J Natl Cancer Inst. 1996;88:340-348. PMID: 8609642.
- Freudenheim JL, Marshall, JR, Graham S, Hellmann R, Vena JE, Bandera E, Muti P, Swanson M, Nemoto T. Exposure to breastmilk in infancy and the risk of breast cancer. Epidemiol. 1994;5:324-31. PMID: 8038247.
- Freudenheim JL, Graham S, Marshall JR, Haughey BP, Cholewinski S, Wilkinson G. Folate intake and carcinogenesis of the colon and rectum. Int J Epidemiol 1991;20:368-74. PMID: 1917236.