Prerequisites: EEH 501, EEH 502, EEH 505, and STA 527
An overview of the field of genetic epidemiology including how to study the genetic causes of phenotypic variation. Topics include human genetics, molecular genetics, and population genetics as they apply to the conduct of a genetic epidemiology study. The concepts of heritability and linkage disequilibrium are covered. The course covers aspects of segregation, linkage, and association as they are used in family- and population-based studies to search for disease-associated genes. Current concepts in the genetics of complex traits as well as an exploration of online databases used in genetic epidemiology are included.
This course is designed for advanced doctoral students.