Education
B.S., National Taiwan University (Taipei, Taiwan)
M.S., Cornell University (Ithaca, NY)
Ph.D., Cornell University (Ithaca, NY)
Profile
Graduate faculty with teaching and research responsibilities.
Postdoctoral training in Yale University and University of
Pittsburgh
Research Interests
Phytoestrogen (isoflavone) and health, Nutrition and immune
response, Vitamin C transport and function, Membrane protein
trafficking.
Selected Publications
- Kuo S-M., Huang C-T, Leavitt PS, Chang C-S. (2001) Quercetin cumulatively enhances
copper induction of metallothionein in intestinal cells.
Biol. Trace Element Res. 84: 1-10.
- Kuo S-M., Stout A, Wactawski-Wende J,
Leppert PC. (2002) Ascorbic acid status in postmenopausal
women with hormone replacement therapy. Maturitas 41: 51-60.
- Peng I-W, Kuo S-M. (2003) Flavonoids
inhibit lipid peroxidation of intestinal cells at physiological
concentrations in a structure-dependent pattern. J. Nutr.
133: 2184-2187.
- Hua P, Tsai W-J, Kuo S-M. (2003)
Estrogen response element-independent regulation of gene
expression by genistein in intestinal cells. Biochim. Biophys.
Acta 1627: 63-70.
- Paradkar PN, Blum PS, Berhow MA, Baumann H, Kuo S-M. (2004) Dietary isoflavones suppress
endotoxin-induced inflammatory reaction in liver and intestine.
Cancer Lett. 215: 21-28.
- Kuo S-M, Tan D, Boyer JC.
(2004) Cellular vitamin C accumulation in the presence of
copper. Biol. Trace Elem. Res. 100: 125-136.
- Kuo S-M, MacLean ME, McCormick K, Wilson JX.(2004) Gender and sodium-ascorbate transporter
isoforms determine ascorbate concentrations in mice. J.
Nutr. 134: 2216-2221.
- Boyer JC, Campbell CE, Sigurdson WJ, Kuo S-M. (2005) Polarized localization of vitamin C
transporters, SVCT1 and SVCT2, in epithelial cells. Biochem.
Biophys. Res. Commun. 334: 150-156.
- Kuo S-M, Tan C-H, Dragan M, Wilson JX. (2005) Endotoxin increases ascorbate recycling
and concentration in mouse liver. J.Nutr. 135: 2411-2416.
- Intra, J. & S.-M. Kuo (2007) Physiological levels of tea catechins increase intracellular lipid antioxidant activity of vitamin C and vitamin E in human intestinal Caco-2 cells. Chemico-Biol. Interactions 169: 91-99.
- Varma, S., C. E. Campbell, & S.-M. Kuo (2008) Functional role of conserved transmembrane segment 1 residues in human sodium-dependent vitamin C transporters. Biochemistry 47:2952-2960.
- Varma, S., Sobey, K., C. E. Campbell, & S.-M. Kuo (2009) Hierarchal contribution of N- and C-terminal sequences to the differential localization of homologous sodium-dependent vitamin C transporters, SVCT1 and SVCT2, in MDCK cells. Biochemistry 48: 2969-2980.
Professional Affiliations
American Association for Cancer Research, American Society
for Biochemistry & Molecular Biology, American Society
for Nutritional Sciences
Faculty Links
|
